{"id":115721,"date":"2024-01-19T12:08:16","date_gmt":"2024-01-19T17:08:16","guid":{"rendered":"https:\/\/paginiromanesti.ca\/?p=115721"},"modified":"2024-01-19T12:08:16","modified_gmt":"2024-01-19T17:08:16","slug":"tratament-impotriva-cancerului-bazat-anticorp-modificat-dezvoltat-cercetatori-israelieni","status":"publish","type":"post","link":"https:\/\/paginiromanesti.ca\/2024\/01\/19\/tratament-impotriva-cancerului-bazat-anticorp-modificat-dezvoltat-cercetatori-israelieni\/","title":{"rendered":"Un nou tratament \u00eempotriva cancerului bazat pe un anticorp modificat, dezvoltat de cercet\u0103tori israelieni"},"content":{"rendered":"<p><strong>Oamenii de \u015ftiin\u0163\u0103 israelieni au dezvoltat un nou anticorp care creeaz\u0103 un r\u0103spuns imunitar puternic \u00eempotriva cancerului, a anun\u0163at joi Institutul de \u015etiin\u0163\u0103 Weizmann (WIS) din Israel, transmite agen\u0163ia Xinhua.<\/strong><\/p>\n<p>Noua realizare imunoterapeutic\u0103, descris\u0103 \u00eentr-un studiu\u00a0<a href=\"https:\/\/www.cell.com\/fulltext\/S0092-8674(23)01343-0\" target=\"_blank\" rel=\"noopener\">publicat \u00een jurnalul \u015ftiin\u0163ific Cell<\/a>, \u00eembun\u0103t\u0103\u0163e\u015fte comunicarea dintre celulele imunitare \u015fi poate conduce la terapii inovatoare \u00eempotriva cancerului \u015fi a bolilor autoimune, a precizat WIS \u00eentr-un comunicat.<\/p>\n<p>Cercet\u0103torii au descoperit c\u0103 celulele imunitare T ajung la epuizare \u015fi \u00ee\u015fi pierd eficacitatea \u00een lupta cu tumorile canceroase \u00een cazul \u00een care nu beneficiaz\u0103 de un sprijin stimulativ din partea celulelor dendritice, cu rol important \u00een sistemul imunitar, scrie <a href=\"https:\/\/www.agerpres.ro\/\" rel=\"nofollow noopener\" target=\"_blank\">Agerpres<\/a>.<\/p>\n<p>Prin urmare, tratamentele obi\u015fnuite folosite \u00een imunoterapie sunt ineficiente \u00een cazul multor pacien\u0163i, deoarece zonele tumorale ale acestora nu au celule imune dendritice, \u00een timp ce la al\u0163i pacien\u0163i eficacitatea este de scurt\u0103 durat\u0103.<\/p>\n<p>Echipa a modificat cu ajutorul ingineriei genetice anticorpul cu dou\u0103 bra\u0163e, denumit BiCE (Bispecific DC-T Cell Engager), un bra\u0163 bloc\u00e2nd receptorul d\u0103un\u0103tor care epuizeaz\u0103 celulele T, \u00een timp ce cel\u0103lalt bra\u0163 recruteaz\u0103 celula dendritic\u0103 esen\u0163ial\u0103.<\/p>\n<p>\u00cen cadrul experimentelor efectuate pe \u015foareci, cercet\u0103torii au constatat c\u0103 anticorpul a \u00eencetinit dezvoltarea tumorilor \u00een cazuri de cancer pulmonar, de piele \u015fi mamar, transmite <a href=\"https:\/\/www.agerpres.ro\/\" rel=\"nofollow noopener\" target=\"_blank\">Agerpres<\/a>.<\/p>\n<p>\u00cen plus, s-a descoperit c\u0103 noul anticorp poate preveni o reapari\u0163ie a cancerului, l\u0103s\u00e2nd \u00een urm\u0103 celule imunitare care \u00ee\u015fi &#8220;amintesc&#8221; cum s\u0103 identifice tumorile \u015fi r\u0103spund \u00een consecin\u0163\u0103.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Oamenii de \u015ftiin\u0163\u0103 israelieni au dezvoltat un nou anticorp care creeaz\u0103 un r\u0103spuns imunitar puternic \u00eempotriva cancerului, a anun\u0163at joi Institutul de \u015etiin\u0163\u0103 Weizmann (WIS) din Israel, transmite agen\u0163ia Xinhua. Noua realizare imunoterapeutic\u0103, descris\u0103 \u00eentr-un studiu\u00a0publicat \u00een jurnalul \u015ftiin\u0163ific Cell, \u00eembun\u0103t\u0103\u0163e\u015fte comunicarea dintre celulele imunitare \u015fi poate conduce la terapii inovatoare \u00eempotriva cancerului \u015fi a [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":114787,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false}}},"categories":[54],"tags":[747,6493],"jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/paginiromanesti.ca\/wp-content\/uploads\/2023\/08\/sddefault-1.jpg","jetpack_shortlink":"https:\/\/wp.me\/p9PoWe-u6t","_links":{"self":[{"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/posts\/115721"}],"collection":[{"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/comments?post=115721"}],"version-history":[{"count":0,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/posts\/115721\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/media\/114787"}],"wp:attachment":[{"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/media?parent=115721"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/categories?post=115721"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/tags?post=115721"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}