{"id":49346,"date":"2019-03-08T14:41:12","date_gmt":"2019-03-08T19:41:12","guid":{"rendered":"https:\/\/paginiromanesti.ca\/?p=49346"},"modified":"2019-03-08T14:41:12","modified_gmt":"2019-03-08T19:41:12","slug":"rechinul-posibil-aliat-lupta-impotriva-cancerului","status":"publish","type":"post","link":"https:\/\/paginiromanesti.ca\/2019\/03\/08\/rechinul-posibil-aliat-lupta-impotriva-cancerului\/","title":{"rendered":"Rechinul alb, un posibil aliat \u00een lupta \u00eempotriva cancerului"},"content":{"rendered":"<h2>Marele rechin alb ar putea s\u0103 se dovedeasc\u0103 \u00een viitorul apropiat un salvator nea\u015fteptat de vie\u0163i umane, datorit\u0103 genomului s\u0103u uria\u015f, care con\u0163ine propriet\u0103\u0163i extraordinare, au anun\u0163at oamenii de \u015ftiin\u0163\u0103 american.<\/h2>\n<div class=\"getty aligncenter\"><a id=\"PXC1dqo8Tax5REryl1Ihyg\" class=\"gie-single\" href=\"http:\/\/www.gettyimages.com\/detail\/611667460\" target=\"_blank\" style=\"color:#a7a7a7;text-decoration:none;font-weight:normal !important;border:none;display:inline-block;\" rel=\"noopener\">Embed from Getty Images<\/a><script>window.gie=window.gie||function(c){(gie.q=gie.q||[]).push(c)};gie(function(){gie.widgets.load({id:'PXC1dqo8Tax5REryl1Ihyg',sig:'cn18ulUdWhrPrDLloZeySAm5opwBVUaAZ5hZq67CC-U=',w:'594px',h:'396px',items:'611667460',caption: false ,tld:'com',is360: false })});<\/script><script src='\/\/embed-cdn.gettyimages.com\/widgets.js' charset='utf-8' async><\/script><\/div>\n<p>Prima &#8220;hart\u0103&#8221; a ADN-ului acestei specii marine a dezv\u0103luit o multitudine de muta\u0163ii care asigur\u0103 protec\u0163ie \u00eempotriva cancerului \u015fi a unor boli asociate procesului de \u00eemb\u0103tr\u00e2nire \u015fi care stimuleaz\u0103 capacit\u0103\u0163ile de vindecare a r\u0103nilor.<\/p>\n<p>Exper\u0163ii sunt de p\u0103rere c\u0103 o mai bun\u0103 \u00een\u0163elegere a modului \u00een care a evoluat rechinul alb pentru a \u00ee\u015fi men\u0163ine genomul stabil \u015fi pentru a rezista la anumite boli ar putea s\u0103 duc\u0103 la dezvoltarea unor noi tratamente de prelungire a vie\u0163ii umane.<\/p>\n<p>\u201eInstabilitatea genomului este o chestiune foarte important\u0103 \u00een cazul multor boli umane grave&#8221;, a declarat unul dintre coautorii studiului. \u201eAcum am descoperit c\u0103 natura a dezvoltat strategii inteligente pentru a men\u0163ine stabilitatea genomurilor acestor rechini, vie\u0163uitoare cu corpuri mari \u015fi cu durate de via\u0163\u0103 \u00eendelungate&#8221;, a ad\u0103ugat el.<\/p>\n<div class=\"getty aligncenter\"><a id=\"kOnwqRzfS-J45IbIwrlmQQ\" class=\"gie-single\" href=\"http:\/\/www.gettyimages.com\/detail\/611542026\" target=\"_blank\" style=\"color:#a7a7a7;text-decoration:none;font-weight:normal !important;border:none;display:inline-block;\" rel=\"noopener\">Embed from Getty Images<\/a><script>window.gie=window.gie||function(c){(gie.q=gie.q||[]).push(c)};gie(function(){gie.widgets.load({id:'kOnwqRzfS-J45IbIwrlmQQ',sig:'F7DT63uARcNGOHXAfzGdKL3Vkf8Jcd0TMospCfc_--w=',w:'594px',h:'396px',items:'611542026',caption: false ,tld:'com',is360: false })});<\/script><script src='\/\/embed-cdn.gettyimages.com\/widgets.js' charset='utf-8' async><\/script><\/div>\n<p>\u201e\u00cenc\u0103 mai avem foarte multe lucruri de \u00eenv\u0103\u0163at de la aceste minuni ale evolu\u0163iei speciilor, inclusiv informa\u0163ii care au poten\u0163ialul de a fi utilizate \u00een lupta contra cancerului \u015fi a bolilor asociate procesului de \u00eemb\u0103tr\u00e2nire \u015fi care pot s\u0103 amelioreze tratamentele de vindecare a r\u0103nilor la pacien\u0163i umani, pe m\u0103sur\u0103 ce vom descoperi modul \u00een care rechinul alb reu\u015fe\u015fte s\u0103 fac\u0103 aceste lucruri&#8221;, a explicat acela\u015fi cercet\u0103tor.<\/p>\n<p>Descifrarea codului genetic al rechinului alb a dezv\u0103luit, de asemenea, dimensiunea crescut\u0103 pe care o are genomul acestui pr\u0103d\u0103tor marin.<\/p>\n<p>El con\u0163ine aproximativ 4,63 miliarde de &#8220;perechi de baze&#8221;, unit\u0103\u0163ile chimice ale ADN-ului, fapt care \u00eel face s\u0103 fie de 1,5 ori mai mare dec\u00e2t omologul s\u0103u uman.<\/p>\n<p>\u00cen ADN-ul rechinului alb se afl\u0103 circa 24.500 de gene care codific\u0103 proteine, \u00een compara\u0163ie cu cele 19.000-20.000 existente, \u00een medie, \u00een genomul uman.<\/p>\n<p>Rechinii din specia &#8220;marele alb&#8221;, care ating o lungime de p\u00e2n\u0103 la 20 de metri \u015fi o greutate de p\u00e2n\u0103 la trei tone, sunt uria\u015fi str\u0103vechi care tr\u0103iesc pe Terra de cel pu\u0163in 16 milioane de ani.<\/p>\n<p>De-a lungul timpului, ei au adoptat numeroase modific\u0103ri moleculare \u00een cadrul genelor asociate cu repararea ADN-ului \u015fi cu toleran\u0163a la deterior\u0103rile genetice, au explicat autorii studiului.<\/p>\n<p>\u00cen contrast, oamenii prezint\u0103 rate \u00eenalte de instabilitate genomial\u0103, cauzate de deterior\u0103ri succesive ale ADN-ului, considerate vinovate pentru vulnerabilitatea omului \u00een fa\u0163a unor boli asociate \u00eemb\u0103tr\u00e2nirii, precum cancerul, transmite Press Association citat\u0103 de <a href=\"https:\/\/www.agerpres.ro\/\" rel=\"nofollow noopener\" target=\"_blank\">Agerpres<\/a>.<\/p>\n<p>&#8220;Nu numai c\u0103 exist\u0103 un num\u0103r surprinz\u0103tor de mare de gene care asigur\u0103 stabilitatea genomului \u015fi care con\u0163in aceste modific\u0103ri adaptive, dar s-a constatat, de asemenea, o \u00eembog\u0103\u0163ire a mai multor astfel de gene, fapt ce subliniaz\u0103 importan\u0163a pe care o are acest reglaj fin genetic \u00een cazul rechinului alb&#8221;, a explicat profesorul Shivji.<\/p>\n<p>Cercet\u0103torii au descoperit c\u0103 alte muta\u0163ii ale genelor rechinului alb sunt asociate cu procesele implicate \u00een vindecarea r\u0103nilor, inclusiv \u00een coagularea sangvin\u0103. Rechinii sunt renumi\u0163i pentru capacitatea lor impresionant\u0103 de a se vindeca \u00een urma unor r\u0103ni grave.<\/p>\n<p>Studiul a fost publicat \u00een Proceedings of the National Academy of Sciences.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Marele rechin alb ar putea s\u0103 se dovedeasc\u0103 \u00een viitorul apropiat un salvator nea\u015fteptat de vie\u0163i umane, datorit\u0103 genomului s\u0103u uria\u015f, care con\u0163ine propriet\u0103\u0163i extraordinare, au anun\u0163at oamenii de \u015ftiin\u0163\u0103 american. Prima &#8220;hart\u0103&#8221; a ADN-ului acestei specii marine a dezv\u0103luit o multitudine de muta\u0163ii care asigur\u0103 protec\u0163ie \u00eempotriva cancerului \u015fi a unor boli asociate procesului [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":49349,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"Marele rechin alb ar putea s\u0103 se dovedeasc\u0103 \u00een viitorul apropiat un salvator nea\u015fteptat de vie\u0163i umane, datorit\u0103 genomului s\u0103u uria\u015f, care con\u0163ine propriet\u0103\u0163i extraordinare","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false}}},"categories":[54],"tags":[747,2860,4390],"jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/paginiromanesti.ca\/wp-content\/uploads\/2019\/03\/e837b80b2ff1023ecd0b470de7444e90fe76e7d01bb1164595f2c0_640_shark.jpg","jetpack_shortlink":"https:\/\/wp.me\/p9PoWe-cPU","_links":{"self":[{"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/posts\/49346"}],"collection":[{"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/comments?post=49346"}],"version-history":[{"count":0,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/posts\/49346\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/media\/49349"}],"wp:attachment":[{"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/media?parent=49346"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/categories?post=49346"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/paginiromanesti.ca\/wp-json\/wp\/v2\/tags?post=49346"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}